Product Description
Cassia seed extract is a concentrated bioactive compound obtained through modern extraction techniques (e.g., supercritical CO₂, high-pressure homogenization, ethanol extraction). Traditionally used in Chinese medicine for liver detoxification, vision improvement, and laxative effects, modern research confirms its efficacy in lipid reduction, uric acid control, and antioxidant activity.
Technical Specifications
1.Extraction Methods
Conventional Methods
Water Decoction: Simple but inefficient, suitable only for water-soluble components.
Ethanol Extraction:
Uses 76–95% ethanol with repeated heat reflux (3 cycles × 3 hours) to enhance anthraquinone yield.
Ideal for lipid-soluble compounds (e.g., cassiasides).
Advanced Extraction Technologies
Supercritical CO₂ Extraction:
Conditions: 25–35 MPa, 45–55°C, 60–120 min; isolates fatty oils while preserving heat-sensitive components.
Combined with high-pressure low-temperature continuous extraction (25–35 MPa, 25–35°C) to boost flavonoid/polysaccharide yields (>65%).
High-Pressure Homogenization (HPH):
200–400 MPa pressure disrupts cell walls via cavitation/shear forces, increasing polysaccharide yield by 50% vs. traditional methods.
Low-temperature processing (<40°C) prevents thermal degradation.
Ultrasound-Assisted Extraction (UAE):
Paired with deep eutectic solvents (DES) (e.g., choline chloride-ethylene glycol); optimized at 480 W, 61°C, 60 min, achieving 15.89% polysaccharide yield.
Purification & Concentration
Macroporous Resin Adsorption: Enriches anthraquinones (up to 4% total content).
Reverse Osmosis Membrane Concentration: Reduces solvent residues, improves purity.
2.Quality Control
Analytical Methods:
HPLC: Quantifies chrysophanol, obtusin, etc.
UPLC-Q-TOF/MS: Metabolomics studies (e.g., uric acid-lowering mechanisms).
Specifications: Total anthraquinones 0.5–4%, water-soluble powder (4:1 or 10:1 concentrate).
Product Advantages
High Bioactivity:
Lipid-lowering: Inhibits cholesterol absorption (e.g., Shanzha lipid-lowering pills with cassia/hawthorn synergy).
Uric acid reduction: Aqueous extract modulates urinary metabolites to lower uric acid.
Antioxidant: Flavonoids scavenge free radicals, protecting hepatocytes (validated in HepG2 models).
Safety: Recognized as food-medicine dual-use with minimal side effects (anthraquinone dosage controlled).
Innovative Processing: HPH and supercritical CO₂ maximize yield and preserve actives.
Applications
Pharmaceuticals:
Lipid-lowering drugs (e.g., compound cassia seed tablets).
Uric acid-lowering formulations (patented aqueous extracts).
Nutraceuticals:
Weight management (laxative effect), eye health blends (with lutein).
Cosmetics:
Oil-control and anti-acne products (sebum inhibition).
Animal Feed Additives: Enhances immunity.
Packing & Storage
- Packing: 1kg/foil bag, 25kg/fiber drum (customizable)
- Storage: Store in a cool, dry place, sealed and protected from light
- Shelf Life: 24 months (under unopened conditions)
One stop service
Raw Material → Powder → Extract → Finished OEM Products
Save 20% on Cost, Traceable Quality!
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