
Product Discription
Milk Thistle is a traditional European hepatoprotective herb. Its active compound silymarin is recognized by both the US Pharmacopeia (USP) and European Pharmacopoeia (EP) as a liver protectant. Modern research confirms its antioxidant, anti-fibrotic, and hepatocyte-regenerating properties, making it a clinically supported adjuvant for alcoholic liver disease and non-alcoholic fatty liver disease (NAFLD).
Key Active Components:
Silymarin (≥30%-80%)
Silybin (Core component, 50%-70% of silymarin)
Flavonoids (e.g., Quercetin)
Unsaturated Fatty Acids (Linoleic acid, Oleic acid)
Physical Properties:
Appearance: Pale yellow to brown powder (seed extract)
Odor: Slightly bitter
Solubility: Poor water solubility; requires phospholipid complexes (e.g., Phytosome®) for enhanced bioavailability
Technical Analysis
Extraction Processes:
Ethanol extraction & purification: Yields standardized silymarin (30%-80%)
Phospholipid complex technology (e.g., Siliphos®): Enhances bioavailability 10-fold vs conventional extracts
Nano-emulsification: Solves water solubility issues for injectable formulations
Quality Control:
HPLC assay: Silymarin content (USP standard ≥30%)
Heavy metals/pesticides: Complies with EP/FDA standards
Microbial limits: Meets GMP requirements
Technical Parameters:
Phospholipid complex particle size: ≤100nm
Standard powder mesh size: 200-400
Key Advantages
Gold Standard Liver Protection:
Multi-mechanism Hepatoprotection:
Inhibits hepatic stellate cell activation (anti-fibrotic)
Increases glutathione (GSH) levels by >30%
Substantial Clinical Evidence:
Improves ALT/AST in NAFLD patients (meta-analysis of clinical trials)
Excellent Safety Profile:
Well-tolerated in long-term use (6-month clinical studies)
Applications
Pharmaceuticals:
Liver disease adjuvants (e.g., Legalon®)
Alcohol detox tablets
Nutraceuticals:
Alcoholic liver support capsules
Detox blends (with curcumin)
Cosmeceuticals:
Anti-pollution serums (urban smog protection)
Brightening masks (reduces liver spots)
Animal Health:
Pet liver support formulas
Mycotoxin detoxifiers in livestock
Specialty Uses:
Chemotherapy-induced liver injury prevention
Occupational chemical exposure protection
Packing & Storage
- Packing: 1kg/foil bag, 25kg/fiber drum (customizable)
- Storage: Store in a cool, dry place, sealed and protected from light
- Shelf Life: 24 months (under unopened conditions)

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